Central Dogma & DNA Variations ＤＮ Ａ mRNA Peptide Transcription Translation Transcription initiation point Transcription termination point Splicing and mRNA maturation Translation initiation point Codon triplets Translation termination point Variations Post-translational peptide modifications Molecules
Not one way, but Multiple Bifurcations Sequence (qualitative) variations, quantitative variations, Chrono-spatial variations ＤＮＡ ｍＲＮＡ１ ｍＲＮＡ２ Ｐｅｐｔｉｄｅ１ Ｐｅｐｔｉｄｅ２ Ｐｅｐｔｉｄｅ３ Ｍｏｌｅｃｕｌｅ３ Ｍｏｌｅｃｕｌｅ２Ｍｏｌｅｃｕｌｅ１ Ｍｏｌｅｃｕｌｅ４ Transcript variations Peptide variations Molecular variations
Susceptible Non-susceptible Association study with DNA-markers DNA-mRNA-Protein relation is not straight, but comparison between DNA variations and phenotype variations bypassing mRNA/proteins simplifies the analysis structure.
Coding-gene World and Variations Coding DNA Coding mRNA Non-coding-gene World and Variations DNA Functional RNA Effects on transcription Effects on translation ?? Effects on phenotypes??
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